{"id":106382,"date":"2023-10-01T09:47:28","date_gmt":"2023-10-01T09:47:28","guid":{"rendered":"https:\/\/dailytalks.org\/?p=106382"},"modified":"2023-10-01T09:47:28","modified_gmt":"2023-10-01T09:47:28","slug":"machine-learning-predicts-cellular-response-to-genetic-perturbation","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=106382","title":{"rendered":"Machine learning predicts cellular response to genetic perturbation"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 17 August 2023; doi:10.1038\/s41587-023-01907-4GEARS, a machine learning model informed by biological knowledge of gene\u2013gene relationships, effectively predicts transcriptional responses to multi-gene perturbations. GEARS can predict the effects of perturbing previously unperturbed genes and detects non-additive interactions, such as synergy, when predicting combinatorial perturbation outcomes&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-023-01907-4\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 17 August 2023; doi:10.1038\/s41587-023-01907-4GEARS, a machine learning model informed by biological<\/p>\n","protected":false},"author":1,"featured_media":106383,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-106382","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation.png",685,602,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation-150x150.png",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation-300x264.png",300,264,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation.png",640,562,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation.png",640,562,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation.png",685,602,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation.png",685,602,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation.png",685,602,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation-685x575.png",685,575,true],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/10\/106382-machine-learning-predicts-cellular-response-to-genetic-perturbation-590x410.png",590,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/106382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=106382"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/106382\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/106383"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=106382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=106382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=106382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}