{"id":153669,"date":"2024-04-16T16:44:32","date_gmt":"2024-04-16T16:44:32","guid":{"rendered":"https:\/\/dailytalks.org\/?p=153669"},"modified":"2024-04-16T16:44:32","modified_gmt":"2024-04-16T16:44:32","slug":"glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=153669","title":{"rendered":"Glia-enriched cortical organoids implanted in mice capture astrocyte diversity"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 14 March 2024; doi:10.1038\/s41587-024-02198-zThe underrepresentation of functional glial cells is a major challenge in brain organoid models. We developed an astroglia-enriched cortical organoid model that allows efficient generation of functional astrocytes and enables the formation of astroglial morphological subclasses with layer-specific gene expression profiles upon transplantation into the mouse brain&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-024-02198-z\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 14 March 2024; doi:10.1038\/s41587-024-02198-zThe underrepresentation of functional glial cells is a<\/p>\n","protected":false},"author":1,"featured_media":153670,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-153669","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity.png",685,656,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity-150x150.png",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity-300x287.png",300,287,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity.png",640,613,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity.png",640,613,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity.png",685,656,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity.png",685,656,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity.png",685,656,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity-685x575.png",685,575,true],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2024\/04\/153669-glia-enriched-cortical-organoids-implanted-in-mice-capture-astrocyte-diversity-590x410.png",590,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/153669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=153669"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/153669\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/153670"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=153669"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=153669"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=153669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}