{"id":166904,"date":"2025-08-05T17:17:42","date_gmt":"2025-08-05T17:17:42","guid":{"rendered":"https:\/\/dailytalks.org\/?p=166904"},"modified":"2025-08-05T17:17:42","modified_gmt":"2025-08-05T17:17:42","slug":"combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-types-regions-and-disease-state","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=166904","title":{"rendered":"Combined single-cell profiling of chromatin\u2013transcriptome and splicing across brain cell types, regions and disease state"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 22 July 2025; doi:10.1038\/s41587-025-02734-5Joint profiling of chromatin and splicing in the brain uncovers shared and distinct patterns&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-025-02734-5\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 22 July 2025; doi:10.1038\/s41587-025-02734-5Joint profiling of chromatin and splicing in the<\/p>\n","protected":false},"author":1,"featured_media":166905,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-166904","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c.jpg",577,685,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c-150x150.jpg",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c-253x300.jpg",253,300,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c.jpg",577,685,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c.jpg",577,685,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c.jpg",577,685,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c.jpg",577,685,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c.jpg",577,685,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c-577x575.jpg",577,575,true],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/08\/166904-combined-single-cell-profiling-of-chromatin-transcriptome-and-splicing-across-brain-cell-t68923cd52f83c-577x410.jpg",577,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/166904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=166904"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/166904\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/166905"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=166904"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=166904"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=166904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}