{"id":186157,"date":"2025-10-28T23:59:41","date_gmt":"2025-10-28T23:59:41","guid":{"rendered":"https:\/\/dailytalks.org\/?p=186157"},"modified":"2025-10-28T23:59:41","modified_gmt":"2025-10-28T23:59:41","slug":"solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=186157","title":{"rendered":"Solution biophysics reveals the polydisperse structure of RNA lipid nanoparticles"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 28 October 2025; doi:10.1038\/s41587-025-02909-0We applied emerging label-free biophysical techniques to map the size, composition and shape of RNA lipid nanoparticles. By linking these physical measurements to gene expression in human T cells and mice, we uncovered structure\u2013activity relationships that guide RNA delivery&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-025-02909-0\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 28 October 2025; doi:10.1038\/s41587-025-02909-0We applied emerging label-free biophysical techniques to map<\/p>\n","protected":false},"author":1,"featured_media":186158,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-186157","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",685,435,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles-150x150.png",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles-300x191.png",300,191,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",640,406,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",640,406,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",685,435,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",685,435,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",685,435,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles.png",685,435,false],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2025\/10\/186157-solution-biophysics-reveals-the-polydisperse-structure-of-rna-lipid-nanoparticles-590x410.png",590,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/186157","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=186157"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/186157\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/186158"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=186157"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=186157"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=186157"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}