{"id":224864,"date":"2026-05-10T01:54:47","date_gmt":"2026-05-10T01:54:47","guid":{"rendered":"https:\/\/dailytalks.org\/?p=224864"},"modified":"2026-05-10T01:54:47","modified_gmt":"2026-05-10T01:54:47","slug":"an-autoimmunity-associated-allele-of-ptpn22-enhances-innate-antiviral-immunity-to-protect-against-acute-coronavirus-infection","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=224864","title":{"rendered":"An autoimmunity-associated allele of PTPN22 enhances innate antiviral immunity to protect against acute coronavirus infection"},"content":{"rendered":"<p>Proceedings of the National Academy of Sciences, Volume 123, Issue 12, March 2026. SignificanceApproximately 5 to 15% of the North American population has thePTPN221858C>T allele, which has been linked with numerous autoimmune diseases and is considered the highest non-HLA risk allele for autoimmunity. Due to this link&#8230;<br \/><a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.2519903123?af=R\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Proceedings of the National Academy of Sciences, Volume 123, Issue 12, March 2026. SignificanceApproximately 5<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-224864","post","type-post","status-publish","format-standard","hentry","category-americas"],"featured_image_urls":{"full":"","thumbnail":"","medium":"","medium_large":"","large":"","1536x1536":"","2048x2048":"","chromenews-featured":"","chromenews-large":"","chromenews-medium":""},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=41\" rel=\"category\">Americas<\/a>","tag_info":"Americas","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/224864","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=224864"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/224864\/revisions"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=224864"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=224864"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=224864"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}