{"id":228703,"date":"2026-05-27T23:54:54","date_gmt":"2026-05-27T23:54:54","guid":{"rendered":"https:\/\/dailytalks.org\/?p=228703"},"modified":"2026-05-27T23:54:54","modified_gmt":"2026-05-27T23:54:54","slug":"mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic-cell-expression","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=228703","title":{"rendered":"mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell expression"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 29 April 2026; doi:10.1038\/s41587-026-03099-zmRNA vaccine efficacy is enhanced by silencing cell-type-specific expression&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-026-03099-z\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 29 April 2026; doi:10.1038\/s41587-026-03099-zmRNA vaccine efficacy is enhanced by silencing cell-type-specific<\/p>\n","protected":false},"author":1,"featured_media":228704,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-228703","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578.jpg",513,685,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578-150x150.jpg",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578-225x300.jpg",225,300,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578.jpg",513,685,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578.jpg",513,685,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578.jpg",513,685,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578.jpg",513,685,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578.jpg",513,685,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578-513x575.jpg",513,575,true],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2026\/05\/228703-mrna-vaccine-immunity-is-enhanced-by-hepatocyte-detargeting-and-not-dependent-on-dendritic6a17845944578-513x410.jpg",513,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/228703","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=228703"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/228703\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/228704"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=228703"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=228703"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=228703"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}