{"id":74571,"date":"2023-06-22T21:45:47","date_gmt":"2023-06-22T21:45:47","guid":{"rendered":"https:\/\/dailytalks.org\/?p=74571"},"modified":"2023-06-22T21:45:47","modified_gmt":"2023-06-22T21:45:47","slug":"combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=74571","title":{"rendered":"Combining reference genomes into a pangenome graph improves accuracy and reduces bias"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 22 May 2023; doi:10.1038\/s41587-023-01828-2Minigraph-Cactus, a method to efficiently combine multiple reference genome assemblies into a pangenome reference graph, can be used to improve accuracy of read mapping and variant calling compared with a single reference in downstream applications&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-023-01828-2\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 22 May 2023; doi:10.1038\/s41587-023-01828-2Minigraph-Cactus, a method to efficiently combine multiple reference<\/p>\n","protected":false},"author":1,"featured_media":74572,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-74571","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias.png",318,685,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias-150x150.png",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias-139x300.png",139,300,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias.png",318,685,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias.png",318,685,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias.png",318,685,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias.png",318,685,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias.png",318,685,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias-318x575.png",318,575,true],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/06\/74571-combining-reference-genomes-into-a-pangenome-graph-improves-accuracy-and-reduces-bias-318x410.png",318,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/74571","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=74571"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/74571\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/74572"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=74571"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=74571"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=74571"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}