{"id":88919,"date":"2023-08-03T19:45:48","date_gmt":"2023-08-03T19:45:48","guid":{"rendered":"https:\/\/dailytalks.org\/?p=88919"},"modified":"2023-08-03T19:45:48","modified_gmt":"2023-08-03T19:45:48","slug":"high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors","status":"publish","type":"post","link":"https:\/\/dailytalks.org\/?p=88919","title":{"rendered":"High-throughput screening of TnpB proteins identifies hypercompact genome editors"},"content":{"rendered":"<p>Nature Biotechnology, Published online: 29 June 2023; doi:10.1038\/s41587-023-01858-wTnpB proteins are hypercompact RNA-guided DNA endonucleases. By systematically mining and characterizing TnpB proteins from the IS605 family, we identified potent genome editors and established a framework for high-throughput annotation and screening of TnpB systems in prokaryotic genomes&#8230;<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41587-023-01858-w\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biotechnology, Published online: 29 June 2023; doi:10.1038\/s41587-023-01858-wTnpB proteins are hypercompact RNA-guided DNA endonucleases. By<\/p>\n","protected":false},"author":1,"featured_media":88920,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-88919","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech"],"featured_image_urls":{"full":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors.png",668,685,false],"thumbnail":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors-150x150.png",150,150,true],"medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors-293x300.png",293,300,true],"medium_large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors.png",640,656,false],"large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors.png",640,656,false],"1536x1536":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors.png",668,685,false],"2048x2048":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors.png",668,685,false],"chromenews-featured":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors.png",668,685,false],"chromenews-large":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors-668x575.png",668,575,true],"chromenews-medium":["https:\/\/dailytalks.org\/wp-content\/uploads\/2023\/08\/88919-high-throughput-screening-of-tnpb-proteins-identifies-hypercompact-genome-editors-590x410.png",590,410,true]},"author_info":{"display_name":"Jonathan Jeriah","author_link":"https:\/\/dailytalks.org\/?author=1"},"category_info":"<a href=\"https:\/\/dailytalks.org\/?cat=35\" rel=\"category\">Tech<\/a>","tag_info":"Tech","comment_count":"0","_links":{"self":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/88919","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=88919"}],"version-history":[{"count":0,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/posts\/88919\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=\/wp\/v2\/media\/88920"}],"wp:attachment":[{"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=88919"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=88919"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dailytalks.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=88919"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}