May 2, 2024
Mathematical modeling of epigenetic gene regulation during cell differentiation

Nature Biotechnology, Published online: 17 October 2022; doi:10.1038/s41587-022-01488-8Cells differentiate to their final fates through sequential epigenetic and transcriptional changes. A mathematical model fit on multi-omic single-cell data yields insights into the temporal relationships between chromatin accessibility and gene expression during cell differentiation…
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