February 12, 2025
Breaking boundaries in whole-body imaging and disease understanding with wildDISCO

Nature Biotechnology, Published online: 10 July 2023; doi:10.1038/s41587-023-01864-yWild three-dimensional imaging of solvent-cleared organs (wildDISCO) uses conventional antibodies for whole-body staining in mice, creating comprehensive biological atlases of nerves, blood vessels and lymphatics. It uncovers pathological changes, such as tertiary lymphoid structures in cancer, and it enables the precise tracking of therapeutic molecules and cells…
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