Nature Biotechnology, Published online: 28 October 2025; doi:10.1038/s41587-025-02906-3We engineered chimeric variants of the Arabidopsis thaliana pattern recognition receptor RLP23 by replacing the C-terminal domain from orthologous proteins in crop species. Expression of these chimeric receptors in tomato markedly enhanced broad-spectrum resistance without compromising yield. Similar results in rice and poplar demonstrate the broad applicability of this engineering strategy…
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